多配體蛋白聚糖4(SDC4)重組蛋白
Recombinant Syndecan 4 (SDC4)
SYND4; Amphiglycan; Ryudocan; Ryudocan core protein
- 編號RPB939Hu01
- 物種Homo sapiens (Human，人)相同的名稱，不同的物種。
- 來源原核表達(dá)
- 宿主E.coli
- 內(nèi)毒素水平<1.0EU/µg(LAL法測定)
- 亞細(xì)胞定位細(xì)胞膜, 分泌
- 預(yù)測分子量17.6kDa
- 實際分子量24kDa(差異分析請參閱說明書)
- 片段與標(biāo)簽Ala18~Glu145 with N-terminal His Tag
- 緩沖液成份20mM Tris, 150mM NaCl緩沖液（pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
- 性狀凍干粉
- 純度> 95%
- 等電點4.5
- 應(yīng)用Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請參見活性蛋白。 - 下載英文說明書 中文說明書
- 規(guī)格10μg50μg200μg1mg5mg
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產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)
Figure. Gene Sequencing (Extract)
SDS-PAGE圖
通過ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
序列
用法
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲存
避免反復(fù)凍融。2-8°C不超過一個月，-80°C不超過12個月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲，損失率低于5%。
增值服務(wù)
相關(guān)產(chǎn)品
| 編號 | 適用物種：Homo sapiens (Human，人) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| APB939Hu01 | 多配體蛋白聚糖4(SDC4)活性蛋白 | Cell?culture;?Activity?Assays. |
| RPB939Hu01 | 多配體蛋白聚糖4(SDC4)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAB939Hu01 | 多配體蛋白聚糖4(SDC4)多克隆抗體 | WB |
| MAB939Hu22 | 多配體蛋白聚糖4(SDC4)單克隆抗體 | WB; IHC; ICC; IP. |
| SEB939Hu | 多配體蛋白聚糖4(SDC4)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMB939Hu | 多配體蛋白聚糖4(SDC4)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻(xiàn)
| 雜志 | 參考文獻(xiàn) |
| Lipids in Health and Disease | The influence of atorvastatin on parameters of inflammation left ventricular function, hospitalizations and mortality in patients with dilated cardiomyopathy–5-year follow-up[PubMed: PMC3641983] |
| The FASEB Journal | Matrix metalloproteinase 9-mediated shedding of syndecan 4 in response to tumor necrosis factor α: a contributor to endothelial cell glycocalyx dysfunction[Pubmed:25122554] |
| Scientific Reports | Biomarkers and Echocardiographic Predictors of Myocardial Dysfunction in Patients with Hypertension[PubMed: 25747153] |
| Int J Mol Sci | The Multi-Biomarker Approach for Heart Failure in Patients with Hypertension[PubMed: 25984599] |
| Biochemical and Biophysical Research Communications | Syndecan-4 shedding impairs macrovascular angiogenesis in diabetes mellitus[Pubmed:27018253] |
| Kidney?International | Aldosterone induces albuminuria via matrix metalloproteinase–dependent damage of the endothelial glycocalyx[Pubmed: 30389198] |