淀粉樣前體蛋白(APP)重組蛋白
Recombinant Amyloid Precursor Protein (APP)
AAA; ABeta; ABPP; AD1; APPI; CVAP; PN2; CTFgamma; Peptidase Nexin-II Alzheimer Disease; Peptidase Nexin-II; Amyloid Beta(A4)Precursor Protein
- 編號RPB020Hu02
- 物種Homo sapiens (Human，人)相同的名稱，不同的物種。
- 來源原核表達
- 宿主E.coli
- 內毒素水平<1.0EU/µg(LAL法測定)
- 亞細胞定位細胞膜, 細胞核, 分泌, 細胞質
- 預測分子量7.9kDa
- 實際分子量12kDa(差異分析請參閱說明書)
- 片段與標簽Asp672~Val711 with N-terminal His Tag
- 緩沖液成份20mM Tris, 150mM NaCl緩沖液（pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
- 性狀凍干粉
- 純度> 95%
- 等電點5.4
- 應用Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請參見活性蛋白。 - 下載英文說明書 中文說明書
- 規(guī)格10μg50μg200μg1mg5mg
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產品包裝(模擬)
產品包裝(模擬)
Figure . Gene Sequencing (extract)
Figure. SDS-PAGE
通過ISO 9001、ISO 13485質量體系認證
序列
用法
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲存
避免反復凍融。2-8°C不超過一個月，-80°C不超過12個月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產生。保質期內，在適當?shù)臈l件下存儲，損失率低于5%。
增值服務
相關產品
| 編號 | 適用物種：Homo sapiens (Human，人) | 應用(僅供研究使用，不用于臨床診斷！) |
| RPB020Hu02 | 淀粉樣前體蛋白(APP)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB020Hu03 | 淀粉樣前體蛋白(APP)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB020Hu01 | 淀粉樣前體蛋白(APP)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAB020Hu01 | 淀粉樣前體蛋白(APP)多克隆抗體 | WB; IHC; ICC; IP. |
| PAB020Hu02 | 淀粉樣前體蛋白(APP)多克隆抗體 | WB; IHC; ICC; IP. |
| PAB020Hu03 | 淀粉樣前體蛋白(APP)多克隆抗體 | WB; IHC; ICC; IP. |
| MAB020Hu22 | 淀粉樣前體蛋白(APP)單克隆抗體 | WB; IHC; ICC; IP. |
| MAB020Hu23 | 淀粉樣前體蛋白(APP)單克隆抗體 | WB; IHC; ICC; IP. |
| WEB020Hu | 淀粉樣前體蛋白(APP)檢測試劑盒(酶聯(lián)免疫吸附試驗法,寬范圍) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SEB020Hu | 淀粉樣前體蛋白(APP)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCB020Hu | 淀粉樣前體蛋白(APP)檢測試劑盒(化學發(fā)光免疫分析法) | Chemiluminescent immunoassay for Antigen Detection. |
| LMB020Hu | 淀粉樣前體蛋白(APP)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻
| 雜志 | 參考文獻 |
| Neurochemistry International | Bilobalide regulates soluble amyloid precursor protein release via phosphatidyl inositol 3 kinase-dependent pathway[ScienceDirect: S0197018611001641] |
| Neuroscience | Substitution of membrane cholesterol with β-sitosterol promotes nonamyloidogenic cleavage of endogenous amyloid precursor protein[Pubmed: 23707801] |
| OncoImmunology | PROOF COVER SHEET[] |
| 臺灣農業(yè)研究 | (臺灣農業(yè)研究67 (4): 355-364) 香菇柄水萃物改善糖尿病降低阿茲海默氏癥罹病風險初探[] |
| Neurotoxicology | Involvement of hippocampal agmatine in β1-42 amyloid induced memory impairment, neuroinflammation and BDNF signaling disruption in mice[Pubmed: 32522471] |
| Metab Brain Dis | Probiotics ameliorates LPS induced neuroinflammation injury on Aβ 1–42, APP, γ-β secretase and BDNF levels in maternal gut microbiota and fetal?…[Pubmed:35312928] |
| Exp Gerontol | The positive impact of 12 weeks of dance and balance training on the circulating amyloid precursor protein and serotonin concentration as well as physical and?…[Pubmed:35217193] |