解整合素金屬蛋白酶17(ADAM17)重組蛋白
Recombinant A Disintegrin And Metalloprotease 17 (ADAM17)
CD156b; TACE; CSVP; Tumor Necrosis Factor,Alpha,Converting Enzyme; Disintegrin and metalloproteinase domain-containing protein 17; Snake venom-like protease
- 編號RPB555Ra01
- 物種Rattus norvegicus (Rat，大鼠)相同的名稱，不同的物種。
- 來源原核表達(dá)
- 宿主E.coli
- 內(nèi)毒素水平<1.0EU/µg(LAL法測定)
- 亞細(xì)胞定位細(xì)胞膜
- 預(yù)測分子量29.6kDa
- 實(shí)際分子量30kDa(差異分析請參閱說明書)
- 片段與標(biāo)簽Leu221~Ser451 with N-terminal His Tag
- 緩沖液成份20mM Tris, 150mM NaCl緩沖液（pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
- 性狀凍干粉
- 純度> 97%
- 等電點(diǎn)5.6
- 應(yīng)用Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請參見活性蛋白。 - 下載英文說明書 中文說明書
- 規(guī)格10μg50μg200μg1mg5mg
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產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)
SDS-PAGE圖
通過ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
序列
用法
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲存
避免反復(fù)凍融。2-8°C不超過一個月，-80°C不超過12個月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲，損失率低于5%。
增值服務(wù)
相關(guān)產(chǎn)品
| 編號 | 適用物種：Rattus norvegicus (Rat，大鼠) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| RPB555Ra01 | 解整合素金屬蛋白酶17(ADAM17)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAB555Ra01 | 解整合素金屬蛋白酶17(ADAM17)多克隆抗體 | WB; IHC; ICC; IP. |
| MAB555Ra21 | 解整合素金屬蛋白酶17(ADAM17)單克隆抗體 | WB; IHC; ICC; IP. |
| SEB555Ra | 解整合素金屬蛋白酶17(ADAM17)檢測試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMB555Ra | 解整合素金屬蛋白酶17(ADAM17)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻(xiàn)
| 雜志 | 參考文獻(xiàn) |
| Int Wound J. | From varices to venous ulceration: the story of chronic venous disease described by metalloproteinases.[Pubmed:26991748] |
| International Wound Journal | From varices to venous ulceration: the story of chronic venous disease described by metalloproteinases[pubmed:26991748] |
| Biomedical Research | ADAM17 regulates TNF-α expression upon lipopolysaccharide stimulation in oral keratinocytes.[pubmed:28637950] |
| Cytometry B Clin Cytom | L‐Selectin Expression Is Influenced by Phosphatase Activity in Chronic Lymphocytic Leukemia[Pubmed: 30729673] |
| Disease Markers | Adamalysines as Biomarkers and a Potential Target of Therapy in Colorectal Cancer Patients: Preliminary Results[Pubmed: 31565100] |
| Chem Biol Interact | PEG-SOD attenuates the mitogenic ERK1/2 signaling cascade induced by cyclosporin A in the liver and kidney of albino mice[Pubmed: 32866465] |
| life | High Levels of TNF-|á and TIM-3 as a Biomarker of Immune Reconstitution Inflammatory Syndrome in People with HIV Infection[] |