頭蛋白(NOG)重組蛋白
Recombinant Noggin (NOG)
SYM1; SYNS1; Synostoses(Multiple)Syndrome 1; Symphalangism 1(Proximal)
- 編號RPC130Mu01
- 物種Mus musculus (Mouse，小鼠)相同的名稱，不同的物種。
- 來源原核表達
- 宿主E.coli
- 內毒素水平<1.0EU/µg(LAL法測定)
- 亞細胞定位分泌
- 預測分子量43.6kDa
- 實際分子量46kDa(差異分析請參閱說明書)
- 片段與標簽Met116~Cys232 with N-terminal His and GST Tag
- 緩沖液成份20mM Tris, 150mM NaCl緩沖液（pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
- 性狀凍干粉
- 純度> 90%
- 等電點10.5
- 應用Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請參見活性蛋白。 - 下載英文說明書 中文說明書
- 規(guī)格10μg50μg200μg1mg5mg
- 價格¥ 878¥ 2196¥ 4392¥ 13176¥ 32940
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產品包裝(模擬)
產品包裝(模擬)
Figure . Gene Sequencing (extract)
SDS-PAGE圖
通過ISO 9001、ISO 13485質量體系認證
序列
用法
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲存
避免反復凍融。2-8°C不超過一個月，-80°C不超過12個月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產生。保質期內，在適當?shù)臈l件下存儲，損失率低于5%。
增值服務
相關產品
| 編號 | 適用物種：Mus musculus (Mouse，小鼠) | 應用(僅供研究使用，不用于臨床診斷！) |
| RPC130Mu01 | 頭蛋白(NOG)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPC130Mu02 | 頭蛋白(NOG)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAC130Mu01 | 頭蛋白(NOG)多克隆抗體 | WB; IHC; ICC; IP. |
| PAC130Mu02 | 頭蛋白(NOG)多克隆抗體 | WB; IHC; ICC; IP. |
| SEC130Mu | 頭蛋白(NOG)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMC130Mu | 頭蛋白(NOG)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
| KSC130Mu01 | 頭蛋白(NOG)檢測試劑盒DIY材料(酶聯(lián)免疫吸附試驗法) | Main materials for "Do It (ELISA Kit) Yourself". |
參考文獻
| 雜志 | 參考文獻 |
| Arthritis Rheumatol | Imbalance between BMP2 and Noggin induces abnormal osteogenic differentiation of mesenchymal stem cells in ankylosing spondylitis[PubMed: 26413886] |
| Arthritis Rheumatol.? | Imbalance Between Bone Morphogenetic Protein 2 and Noggin Induces Abnormal Osteogenic Differentiation of Mesenchymal Stem Cells in Ankylosing Spondylitis[Pubmed:26413886] |
| Clin Exp Pharmacol Physiol. | Oxygen-glucose deprivation preconditioning protects neurons against oxygen-glucose deprivation/reperfusion induced injury via bone morphogenetic protein-7 mediated ERK, p38 and Smad signalling pathways.[Pubmed:26385023] |
| European cells & materials | The BMP2 variant L51P restores the osteogenic differentiation of human mesenchymal stromal cells in the presence of intervertebral disc cells.[pubmed:28266688] |
| Arthritis?&?Rheumatology | mbalance?Between?Bone?Morphogenetic?Protein?2?and?Noggin?Induces?Abnormal?OsteogenicDifferentiation?of?Mesenchymal?Stem Cells in Ankylosing Spondylitis.[pubmed:26413886] |
| Biotechnology and?Applied?Biochemistry | The BMP antagonist Noggin is produced by osteoblasts in response to the presence of prostate cancer cells.[pubmed:28981962] |
| Heliyon | Efficient in vitro delivery of Noggin siRNA enhances osteoblastogenesis[pubmed:29167826] |
| Journal of Cellular Biochemistry | Low‐intensity pulsed ultrasound promotes bone morphogenic protein 9‐induced osteogenesis and suppresses inhibitory effects of inflammatory cytokines on cellular?…[Pubmed: 31006911] |
| Aging Male | Effect of tadalafil on penile nitric oxide synthase and corporal smooth muscle in rats under dutasteride treatment[Pubmed: 32160825] |
| J Reconstr Microsurg | Effect of Simvastatin Use in Free Tissue Transfer: An Experimental Study in a Rat Epigastric Free Flap Model[Pubmed: 31995818] |
| Biochem Biophys Rep | Slow diffusion on the monolayer culture enhances auto/paracrine effects of Noggin in differentiation of human iPS cells induced by BMP[Pubmed:35005256] |