血管細胞粘附分子1(VCAM1)單克隆抗體
Monoclonal Antibody to Vascular Cell Adhesion Molecule 1 (VCAM1)
CD106; INCAM-100; L1CAM
- 編號MAA547Ra23
- 物種Rattus norvegicus (Rat，大鼠)相同的名稱，不同的物種。
- 來源單抗制備
- 宿主小鼠
- 效價(克隆號)D21
- Ig亞型 IgG1 Kappa
- 純化方式蛋白A + 蛋白G親和純化
- 標記物無標記物
- 免疫原RPA547Ra02-血管細胞粘附分子1(VCAM1)重組蛋白
- 緩沖液成份0.01M 磷酸鹽緩沖液（pH7.4，containing 0.05% Proclin-300，50% glycerol）
- 性狀液體
- 濃度1mg/mL
- 且適物種-
- 應(yīng)用WB; IHC; ICC; IP.
如果抗體需用于流式細胞術(shù)，請參見流式抗體。 - 下載英文說明書 中文說明書
- 規(guī)格20μl100μl200μl1ml10ml
- 價格¥ 670¥ 1562¥ 2232¥ 5580¥ 22320
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產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)
Western Blot; Sample: Rat Spleen lysate Primary Ab: 1μg/ml Mouse Anti-Rat VCAM1 Antibody Second Ab: 0.2μg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: SAA544Mu19)
通過ISO 9001、ISO 13485質(zhì)量體系認證
特異性
該抗體是針對VCAM1的小鼠單克隆抗體。在免疫組織化學(xué)染色和免疫印跡實驗中能識別VCAM1。
用法
Western blotting: 0.5-2μg/mL;
Immunohistochemistry: 5-20μg/mL;
Immunocytochemistry: 5-20μg/mL;
Optimal working dilutions must be determined by end user.
儲存
經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復(fù)凍融。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲，損失率低于5%。
贈品
增值服務(wù)
相關(guān)產(chǎn)品
| 編號 | 適用物種：Rattus norvegicus (Rat，大鼠) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| RPA547Ra01 | 血管細胞粘附分子1(VCAM1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA547Ra02 | 血管細胞粘附分子1(VCAM1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAA547Ra01 | 血管細胞粘附分子1(VCAM1)多克隆抗體 | WB; IHC; ICC; IP. |
| PAA547Ra02 | 血管細胞粘附分子1(VCAM1)多克隆抗體 | WB; IHC |
| MAA547Ra23 | 血管細胞粘附分子1(VCAM1)單克隆抗體 | WB; IHC; ICC; IP. |
| MAA547Ra24 | 血管細胞粘附分子1(VCAM1)單克隆抗體 | WB; IHC; ICC; IP. |
| MAA547Ra25 | 血管細胞粘附分子1(VCAM1)單克隆抗體 | WB; IHC; ICC; IP. |
| MAA547Ra22 | 血管細胞粘附分子1(VCAM1)單克隆抗體 | WB |
| MAA547Ra21 | 血管細胞粘附分子1(VCAM1)單克隆抗體 | WB |
| SEA547Ra | 血管細胞粘附分子1(VCAM1)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMA547Ra | 血管細胞粘附分子1(VCAM1)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻
| 雜志 | 參考文獻 |
| Amran et al. Lipids in Health and Disease | Changes in the vascular cell adhesion molecule-1, intercellular adhesion molecule-1 and c-reactive protein following administration of aqueous extract of piper sarmentosum on experimental.[BioMed: 1476511X] |
| Vascular Pharmacology | Long-term ethanol consumption initiates atherosclerosis in rat aorta through inflammatory stress and endothelial dysfunction[ScienceDirect: S1537189112000705] |
| Canadian Journal of Physiology and Pharmacology | Resveratrol abrogates adhesion molecules and protects against TNBS-induced ulcerative colitis in rats.[PubMed: 22029500] |
| British Journal of Medical and Health Sciences | EFFECTS OF ADRIAMYCIN, CISPLATIN, AND 5-FLUOROURACIL ON THE TESTES OF ALBINO RATS[Researchgate: Source] |
| Endocrine Metabolic & Immune Disordors Drug Targets. | Active immunization against tumor necrosis factor-alpha decreases proinflammatory cytokines, oxidative stress mediators and adhesion molecules risk factors in streptozotocin-induced diabetic rats.[Pubmed: 23859636] |
| Atherosclerosis | Increased monocyte adhesion by endothelial expression of VCAM-1 missense variation in vitro [Pubmed: 24075742] |
| Atherosclerosis | Activation of receptor for advanced glycation end products contributes to aortic remodeling and endothelial dysfunction in sinoaortic denervated rats.[Pubmed: 23880178] |
| BioMed research international | Endothelial gene expression and molecular changes in response to radiosurgery in in vitro and in vivo models of cerebral arteriovenous malformations[Pubmed: 24199192] |
| Arch Dis Child | PO-0699 Estimation Of Adhesion Molecules Intrauterine Growth Retardation (iugr) Newborns[Bmj:Source] |
| Arch Dis Child? | PO-0701 Causes Of Fetal Growth Restriction And Early Neonatal Outcome[Bmj:Source] |
| Arch Dis Child | PO-0698 Neonatal Resuscitation Practices In The Delivery Room In India: An Audit Using Videography[Bmj:Source] |
| Naunyn-Schmiedeberg's Archives of Pharmacology | Insights into the antiatherogenic molecular mechanisms of andrographolide against?Porphyromonas gingivalis-induced atherosclerosis in rabbits[Pubmed:25172523] |
| Nutr Res. | Curcumin attenuates adhesion molecules and matrix metalloproteinase expression in hypercholesterolemic rabbits[Pubmed:25282128] |
| Alexandria Journal of Medicine | Effect of consumption of fresh and heated virgin coconut oil on the blood pressure and inflammatory biomarkers: An experimental study in Sprague Dawley rats[Sciencedirect:S2090506814000268] |
| Canadian Journal of Physiology and Pharmacology | Effect of magnesium sulfate and thyroxine on inflammatory markers in a rat model of hypothyroidism[Doi: Abs] |
| Hum Exp Toxicol | Effect of agmatine on experimental vascular endothelial dysfunction[PubMed: 26424770] |
| International Journal of Food Sciences and Nutrition | Serum lipid profile and inflammatory markers in the aorta of cholesterol-fed rats supplemented with extra virgin olive oil, sunflower oils and oil-products[PubMed: 26401576] |
| J Trace Elem Med Biol | Comparative angioprotective effects of magnesium compounds[PubMed: 25127069] |
| J Mol Cell Cardiol | Diverse contribution of bone marrow-derived late-outgrowth endothelial progenitor cells to vascular repair under pulmonary arterial hypertension and arterial neointimal formation[PubMed: 26231083] |
| Endocrine | Effects of glucagon-like peptide-1 on advanced glycation endproduct-induced aortic endothelial dysfunction in streptozotocin-induced diabetic rats: possible roles of Rho kinase- and AMP kinase-mediated nuclear factor κB signaling pathways[Pubmed:26758998] |
| Mol Neurobiol | A Therapeutic Insight of Niacin and Coenzyme Q10 Against Diabetic Encephalopathy in Rats[Pubmed:26867655] |
| Pakistan journal of pharmaceutical sciences | Changes in blood pressure, vascular reactivity and inflammatory biomarkers following consumption of heated corn oil.[pubmed:29084680] |
| Acta Biochim Biophys Sin | Therapeutic potential of mesenchymal stem cells in acute kidney injury is affected by administration timing[pubmed:28338909] |
| Experimental and Therapeutic Medicine | Epigallocatechin?3?gallate attenuates neointimal hyperplasia in a rat model of carotid artery injury by inhibition of high mobility group box 1 expression[pubmed:28962112] |
| Experimental Parasitology | Adhesion molecules, chemokines and matrix metallo-proteinases response after albendazole and albendazole plus steroid therapy in swine neurocysticercosis[pubmed:28821422] |
| Evidence-Based Complementary and Alternative Medicine | BuShenKangShuai tablet reduces atherosclerotic lesion by improving blood lipids metabolism and inhibiting inflammatory response via TLR4 and NF-κB signaling pathway[journals:1758383] |
| Journal of Chromatography A | Application of a new procedure for liquid chromatography/mass spectrometry profiling of plasma amino acid-related metabolites and untargeted shotgun proteomics to identify mechanisms and biomarkers of calcific aortic stenosis[S0021967317311858] |
| International Journal of?Clinical?and Experimental Pathology | Protective effect of high mobility group box-1 silence on diabetic retinopathy: an in vivo study[ISSN:1936-2625/IJCEP0055881] |
| ResearchGate | Significance of Soluble Endoglin as a Possible Marker of Cardiovascular Disease in Type 2 Diabetic Patients[315113405] |
| Regenerative Biomaterials | The directional migration and differentiation of mesenchymal stem cells toward vascular endothelial cells stimulated by biphasic calcium phosphate ceramic[10.1093/rb/rbx028] |
| Anesthesiology | Vasculotide, an angiopoietin-1 mimetic, restores microcirculatory perfusion and microvascular leakage and decreases fluid resuscitation requirements in?…[Pubmed:28968277] |
| PLoS Neglected Tropical Diseases | Characterization of the rhesus macaque (Macaca mulatta) scrub typhus model: Susceptibility to intradermal challenge with the human pathogen Orientia?…[Pubmed:29522521] |
| Life Sciences | Nephroprotective effect of saxagliptin against gentamicin-induced nephrotoxicity, emphasis on anti-oxidant, anti-inflammatory and anti-apoptic effects[Pubmed:30012474] |
| Evidence-based?Complementary and Alternative?Medicine | Bushenkangshuai Tablet Reduces Atherosclerotic Lesion by Improving Blood Lipids Metabolism and Inhibiting Inflammatory Response via TLR4 and NF-κB Signaling?…[Pubmed:29619063] |
| Nutrition?&?Metabolism | L-Carnitine Supplementation Increases Trimethylamine-N-Oxide but not Markers of Atherosclerosis in Healthy Aged Women[Pubmed: 30485835] |
| Cytokine | Intercellular adhesion molecule-1 (ICAM-1) associates with 24-hour ambulatory blood pressure variability in type 2 diabetes and controls[Pubmed: 30716657] |
| Anticancer?Research | Effect of Radiation on the Expression of CVD-related miRNAs, Inflammation and Endothelial Dysfunction of HUVECs[Pubmed: 30711956] |
| European?Journal of Pharmacology | The cordycepin derivative IMM-H007 improves endothelial dysfunction by suppressing vascular inflammation and promoting AMPK-dependent eNOS activation in?…[Pubmed: 30826323] |
| international journal of molecular sciences | Anti-Inflammatory and Anti-Apoptotic Effects of Stybenpropol A on Human Umbilical Vein Endothelial Cells[Pubmed: 31671764] |
| Archives of Insect Biochemistry and Physiology | Vanadyl sulphate ameliorates biomarkers of endothelial injury and coagulation and thrombosis in a rat model of hyperglycaemia[Pubmed: 31774317] |
| BMC Endocrine Disorders | The role of the adipocytokines vaspin and visfatin in vascular endothelial function and insulin resistance in obese children[Pubmed: 31771561] |
| Scientific Reports | Association between Upper-airway Surgery and Ameliorative Risk Markers of endothelial function in obstructive Sleep Apnea[Pubmed: 31882827] |
| BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE | Endothelial epithelial sodium channel involves in high-fat diet-induced atherosclerosis in low-density lipoprotein receptor-deficient mice[Pubmed: 33065235] |
| Antioxidants (Basel) | Anti-Atherogenic Effects of Orlistat on Obesity-Induced Vascular Oxidative Stress Rat Model[33562069] |
| Sci. Pharm | Dehydroepiandrosterone (DHEA) Improves the Metabolic and Haemostatic Disturbances in Rats with Male Hypogonadism[] |
| Journal of the South African Veterinary Association | Circulating markers of endothelial activation in canine parvoviral enteritis[] |