T-細(xì)胞可誘導(dǎo)共刺激分子(ICOS)重組蛋白
Recombinant Inducible T-Cell Co Stimulator (ICOS)
CD278; AILIM; Inducible T-Cell Costimulator; Activation-Inducible Lymphocyte Immunomediatory Molecule
- 編號(hào)RPA777Hu01
 - 物種Homo sapiens (Human,人)相同的名稱,不同的物種。
 - 來(lái)源原核表達(dá)
 - 宿主E.coli
 - 內(nèi)毒素水平<1.0EU/µg(LAL法測(cè)定)
 - 亞細(xì)胞定位細(xì)胞膜, 分泌
 - 預(yù)測(cè)分子量48.1kDa
 - 實(shí)際分子量48kDa(差異分析請(qǐng)參閱說(shuō)明書(shū))
 - 片段與標(biāo)簽Phe31~Lys190 with N-terminal His and GST Tag
 - 緩沖液成份20mM Tris, 150mM NaCl緩沖液(pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300)
 - 性狀凍干粉
 - 純度> 90%
 - 等電點(diǎn)8.3
 - 應(yīng)用Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白,請(qǐng)參見(jiàn)活性蛋白。 - 下載英文說(shuō)明書(shū) 中文說(shuō)明書(shū)
 - 規(guī)格10μg50μg200μg1mg5mg
 - 價(jià)格¥ 912¥ 2280¥ 4560¥ 13680¥ 34200
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序列

用法
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲(chǔ)存
避免反復(fù)凍融。2-8°C不超過(guò)一個(gè)月,-80°C不超過(guò)12個(gè)月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定,具體方法如下:在37°C孵育48小時(shí),沒(méi)有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi),在適當(dāng)?shù)臈l件下存儲(chǔ),損失率低于5%。
增值服務(wù)
相關(guān)產(chǎn)品
| 編號(hào) | 適用物種:Homo sapiens (Human,人) | 應(yīng)用(僅供研究使用,不用于臨床診斷!) | 
| RPA777Hu01 | T-細(xì)胞可誘導(dǎo)共刺激分子(ICOS)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. | 
| PAA777Hu01 | T-細(xì)胞可誘導(dǎo)共刺激分子(ICOS)多克隆抗體 | WB; IHC; ICC; IP. | 
| FAA777Hu01 | 抗T-細(xì)胞可誘導(dǎo)共刺激分子(ICOS)多克隆抗體 | Flow cytometry. | 
| LAA777Hu81 | T-細(xì)胞可誘導(dǎo)共刺激分子(ICOS)多克隆抗體(異硫氰酸熒光素標(biāo)記) | WB; IHC; ICC; IF. | 
| LAA777Hu71 | T-細(xì)胞可誘導(dǎo)共刺激分子(ICOS)多克隆抗體(生物素標(biāo)記) | WB; IHC; ICC. | 
| FAA777Hu41 | 抗T-細(xì)胞可誘導(dǎo)共刺激分子(ICOS)多克隆抗體(藻紅素標(biāo)記) | Flow cytometry. | 
| FAA777Hu51 | 抗T-細(xì)胞可誘導(dǎo)共刺激分子(ICOS)多克隆抗體(別藻藍(lán)蛋白標(biāo)記) | Flow cytometry. | 
| FAA777Hu81 | 抗T-細(xì)胞可誘導(dǎo)共刺激分子(ICOS)多克隆抗體(異硫氰酸熒光素標(biāo)記) | Flow cytometry. | 
| MAA777Hu22 | T-細(xì)胞可誘導(dǎo)共刺激分子(ICOS)單克隆抗體 | WB; IHC; ICC; IP. | 
| RAA777Hu21 | T-細(xì)胞可誘導(dǎo)共刺激分子(ICOS)重組抗體 | WB; IFC; IHC; IP. | 
| SEA777Hu | T-細(xì)胞可誘導(dǎo)共刺激分子(ICOS)檢測(cè)試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) | Enzyme-linked immunosorbent assay for Antigen Detection. | 
| LMA777Hu | T-細(xì)胞可誘導(dǎo)共刺激分子(ICOS)等多因子檢測(cè)試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. | 
參考文獻(xiàn)
| 雜志 | 參考文獻(xiàn) | 
| Archives of Dermatological Research | Increased production of soluble inducible costimulator in patients with diffuse cutaneous systemic sclerosis[Pubmed: 23053221] | 
| DNA Cell Biol. | Effect of soluble inducible costimulator level and its polymorphisms on age-related macular degeneration.[Pubmed: 24083358] | 
| Rheumatology | Augmented ICOS expression in patients with early diffuse cutaneous systemic sclerosis[Pubmed: 23024058] | 
| Br J Haematol | Inducible T‐cell co‐stimulator (ICOS) and ICOS ligand are novel players in the multiple‐myeloma microenvironment[Pubmed:34954822] | 
| Diagnostics (Basel) | Increased Levels of ICOS and ICOSL Are Associated to Pulmonary Arterial Hypertension in Patients Affected by Connective Tissue Diseases[Pubmed:35328257] | 



