生長停滯特異性蛋白6(GAS6)重組蛋白
Recombinant Growth Arrest Specific Protein 6 (GAS6)
AXLLG; AXSF; AXL Stimulatory Factor; AXL receptor tyrosine kinase ligand
- 編號RPA204Mu01
- 物種Mus musculus (Mouse，小鼠)相同的名稱，不同的物種。
- 來源原核表達
- 宿主E.coli
- 內(nèi)毒素水平<1.0EU/µg(LAL法測定)
- 亞細胞定位分泌
- 預(yù)測分子量19.0kDa
- 實際分子量21kDa(差異分析請參閱說明書)
- 片段與標簽Ala483~Gly646 with N-terminal His Tag
- 緩沖液成份磷酸鹽緩沖液（pH7.4，含有 0.01% SKL, 1mM DTT, 5% Trehalose和Proclin300.）
- 性狀凍干粉
- 純度> 97%
- 等電點5.6
- 應(yīng)用Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請參見活性蛋白。 - 下載英文說明書 中文說明書
- 規(guī)格10μg50μg200μg1mg5mg
- 價格¥ 816¥ 2040¥ 4080¥ 12240¥ 30600
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產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)
SDS-PAGE圖
通過ISO 9001、ISO 13485質(zhì)量體系認證
序列
用法
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲存
避免反復凍融。2-8°C不超過一個月，-80°C不超過12個月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當?shù)臈l件下存儲，損失率低于5%。
增值服務(wù)
相關(guān)產(chǎn)品
| 編號 | 適用物種：Mus musculus (Mouse，小鼠) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| RPA204Mu02 | 生長停滯特異性蛋白6(GAS6)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA204Mu01 | 生長停滯特異性蛋白6(GAS6)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAA204Mu01 | 生長停滯特異性蛋白6(GAS6)多克隆抗體 | WB; IHC; ICC; IP. |
| PAA204Mu02 | 生長停滯特異性蛋白6(GAS6)多克隆抗體 | WB; IHC; ICC; IP. |
| SEA204Mu | 生長停滯特異性蛋白6(GAS6)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMA204Mu | 生長停滯特異性蛋白6(GAS6)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻
| 雜志 | 參考文獻 |
| Acta Pharmacol Sin. | Pharmacological evidence: a new therapeutic approach to the treatment of chronic heart failure through SUR2B/Kir6.1 channel in endothelial cells.[pubmed:27890915] |
| Frontiers of Medicine | The effects of Parenteral K1 administration in Pseudoxanthoma elasticum Patients Versus controls. a Pilot study[Pubmed:29713628] |
| Oncotarget | DAPK and CIP2A are involved in GAS6/AXL-mediated Schwann cell proliferation in a rat model of bilateral cavernous nerve injury[Pubmed:29464081] |
| journal of nutritional biochemistry | Gamma-glutamyl carboxylated Gas6 mediates the beneficial effect of vitamin K on lowering hyperlipidemia via regulating the AMPK/SREBP1/PPARα signaling?…[Pubmed: 31226525] |
| CELL DEATH AND DIFFERENTIATION | KPNB1-mediated nuclear translocation of PD-L1 promotes non-small cell lung cancer cell proliferation via the Gas6/MerTK signaling pathway[Pubmed: 33139930] |
| 重度子癇前期患者血清GAS6 與其他炎癥因子的相關(guān)性研究[] | |
| JOURNAL OF NUTRITIONAL BIOCHEMISTRY | Gamma-glutamyl carboxylated Gas6 facilitates the prophylactic effect of vitamin K in inhibiting hyperlipidemia-associated inflammatory pathophysiology via arresting MCP-1/ICAM-1 mediated monocyte-hepatocyte adhesion[33789149] |