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腦源性神經(jīng)營養(yǎng)因子(BDNF)重組蛋白

Recombinant Brain Derived Neurotrophic Factor (BDNF)

Neurotrophin; Abrineurin

  • 腦源性神經(jīng)營養(yǎng)因子(BDNF)重組蛋白產(chǎn)品包裝(模擬)
  • 腦源性神經(jīng)營養(yǎng)因子(BDNF)重組蛋白產(chǎn)品包裝(模擬)
  • RPA011Ra01.jpgFigure. SDS-PAGE
  • Certificate通過ISO 9001、ISO 13485質量體系認證

序列

用法

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

儲存

避免反復凍融。2-8°C不超過一個月，-80°C不超過12個月。

穩(wěn)定性

熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質期內，在適當?shù)臈l件下存儲，損失率低于5%。

參考文獻

雜志參考文獻
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Journal of the Neurological SciencesNeuroprotective effects of adipose-derived stem cells against ischemic neuronal damage in the rabbit spinal cord[ScienceDirect: S0022510X12001219]
International Conference on BioscienceEffect of Benthosemapterotum Peptide on Aging in Mice with Oxidative Damage[Psrcentre: 212059]
Neuroscience LettersChronic stress impairs learning and hippocampal cell proliferation in senescence-accelerated prone mice[ScienceDirect: S0304394010015788]
BioMed Research InternationalNeuroprotective effects of adipose-derived stem cells are maintained for 3 weeks against ischemic damage in the rabbit spinal cord.[NCBI: PMC3925622]
Behavioural Brain ResearchThe effects of Ginkgo biloba extract on cognitive functions in aged female rats: The role of oxidative stress and brain-derived neurotrophic factor[Pubmed:25446810]
Neurochemical ResearchHeme?Oxygenase-1?Protects?Neurons?from?Ischemic?Damage?by?UpreCavia (Guinea pig )lating?Expression?of?Cu,Zn-SuperoxideDismutase,?Catalase, and?Brain-Derived?Neurotrophic?Factor?in the?Rabbit?Spinal?Cord.[Pubmed:26559686]
Exp Ther Med. Effects of docosahexaenoic acid on learning and memory impairment induced by repeated propofol anesthesia in young rats[pmc:PMC4812310]
Genet Mol ResChanges in growth factor levels in the cerebrospinal fluid of autism patients after transplantation of human umbilical cord blood mononuclear cells and umbilical cord-derived mesenchymal stem cells[Pubmed:27323064]
The International Journal af Applied Research in Veterinary MedicineEffect of Sample Time in Clot Tube, Temperature, and Hemolysis Status on Canine Serum Brain-Derived Neurotrophic Factor (BDNF) Concentrations: Preliminary study [articles:Vol14Iss3]
J Chem Neuroanat.Both secreted and the cellular levels of BDNF attenuated due to tau hyperphosphorylation in primary cultures of cortical neurons.[pubmed:27914953]
Int Immunopharmacol.PPARr activation ameliorates postoperative cognitive decline probably through suppressing hippocampal neuroinflammation in aged mice.[pubmed:27940378]
The Journal of Maternal-Fetal & Neonatal MedicineDifferential expression of cord blood neurotrophins in gestational diabetes: the impact of fetal growth abnormalities[pubmed:28081639]
IOS Press Content LibraryAn Intranasal Formulation of Erythropoietin (Neuro-EPO) Prevents Memory Deficits and Amyloid Toxicity in the APPSwe Transgenic Mouse Model of Alzheimer's …[articles:journal-of-alzheimers-disease]
Bipolar DisordersLong‐term lithium treatment increases intracellular and extracellular brain‐derived neurotrophic factor (BDNF) in cortical and hippocampal neurons at subtherapeutic …[bdi.12449]
ElsevierAssociations of blood parameters with age, feed efficiency and sampling routine in young beef bulls[science:article]
journal of?allergy?and?clinical?immunologyWater-soluble chitosan inhibits nerve growth factor and attenuates allergic inflammation in mite allergen–induced allergic rhinitis[pubmed:28412394]
American Journal of Translational ResearchA new comorbidity model and the common pathological mechanisms of migraine and epilepsy[pubmed:28559979]
European Journal of PharmacologyAlpha-asarone attenuates depression-like behavior in nicotine-withdrawn mice: Evidence for the modulation of hippocampal pCREB levels during nicotine-withdrawal.[pubmed:29042206]
Brain,?Behavior, and?ImmunityAn enriched environment restores hepatitis B vaccination-mediated impairments in synaptic function through IFN-γ/Arginase1 signaling[Pubmed:29627530]
Stem?Cell?Research?&?TherapyAutophagy is required for human umbilical cord mesenchymal stem cells to improve spatial working memory in APP/PS1 transgenic mouse model[Pubmed:29335016]
Pharmacological?Research?N-3 PUFA diet enrichment prevents amyloid beta-induced depressive-like phenotype[Pubmed:29203442]
Experimental NeurologyPreterm umbilical cord blood derived mesenchymal stem/stromal cells protect preterm white matter brain development against hypoxia-ischemia[Pubmed:30012511]
NutrientsEarly Life Vitamin C Deficiency Does Not Alter Morphology of Hippocampal CA1 Pyramidal Neurons or Markers of Synaptic Plasticity in a Guinea Pig Model.[Pubmed:29890692]
Neurotoxicity ResearchDelta-9-Tetrahydrocannabinol (?-THC) Induce Neurogenesis and Improve Cognitive Performances of Male Sprague Dawley Rats[Pubmed:28933048]
NeurotoxicologyAmelioration by nitric oxide (NO) mimetics on neurobehavioral and biochemical changes in experimental model of Alzheimer's disease in rats[Pubmed:29522778]
Neuroscience LettersLong term Westernized diet leads to region-specific changes in brain signaling mechanisms[Pubmed:29655945]
Applied?Physiology Nutrition and MetabolismChanges in exercise capacity and serum BDNF following long-term sprint interval training in well-trained cyclists[Pubmed: 30286300]
HeliyonEstablishment and evaluation of a novel mouse model of peri/postmenopausal depression[Doi: 10.1016/j.heliyon.2019.e01195]
BioMed Research InternationalAdministration of Repetitive Transcranial Magnetic Stimulation Attenuates Aβ1-42-Induced Alzheimer's Disease in Mice by Activating β-Catenin Signaling[]
International Journal of Immunopathology and PharmacologyEffect of voluntary running on expression of myokines in brains of rats with depression[Pubmed: 30834799]
American Journal of Emergency?MedicineClinical usefulness of brain-derived neurotrophic factor and visinin-like protein-1 in early diagnostic tests for acute stroke[Pubmed: 30826210]
Neurochemistry InternationalMonoaminergic system is implicated in the antidepressant-like effect of hyperoside and protocatechuic acid isolated from Impatiens glandulifera Royle in mice[Pubmed: 31077758]
REVISTA DA ASSOCIACAO MEDICA BRASILEIRAPhysical Exercise Increased Brain-Derived Neurotrophic Factor in Elderly Population with Depression[Pubmed: 30994834]
Journal of Alzheimer's DiseaseRegular Exercise Enhances Cognitive Function and Intracephalic GLUT Expression in Alzheimer's Disease Model Mice[Pubmed: 31561359]
Biological Trace Element ResearchCognitive Decline of Rats with Chronic Fluorosis Is Associated with Alterations in Hippocampal Calpain Signaling[Pubmed: 31797207]
PsychopharmacologyChronic harmine treatment has a delayed effect on mobility in control and socially defeated rats[Pubmed: 32088835]
Experimental and Therapeutic MedicineInvolvement of neurotrophic signaling in doxorubicin?induced cardiotoxicity[Pubmed: 32010279]
Journal of Critical CareAssociation of neuronal repair biomarkers with delirium among survivors of critical illness[Pubmed: 31896448]
Journal of Clinical NeuroscienceCSF levels of a set of neurotrophic factors (brain-derived neurotrophic factor, nerve growth factor) and neuropeptides (neuropeptide Y, galanin) in epileptic children[Pubmed: 32327377]
MOLECULAR NUTRITION & FOOD RESEARCHHyperlipidemia Down‐Regulate Brain Antioxidant Defense Enzymes and Neurotrophins in Rats: Assessment of the Modulatory Potential of EPA+ DHA and?…[Pubmed: 32918393]
NeuropharmacologyImpaired LTD-like motor cortical plasticity in female patients with major depression disorder[Pubmed: 32791084]
COLLOIDS AND SURFACES B-BIOINTERFACESEffects of gold nanoparticles administration through behavioral and oxidative parameters in animal model of parkinson's disease[Pubmed: 32777662]
NeurotoxicologyInvolvement of hippocampal agmatine in β1-42 amyloid induced memory impairment, neuroinflammation and BDNF signaling disruption in mice[Pubmed: 32522471]
Journal of Veterinary BehaviorComparison of serum brain-derived neurotrophic factor (BDNF) in dogs with and without separation anxiety[]
Food & FunctionNicotinamide riboside alleviates alcohol-induced depression-like behaviours in C57BL/6J mice by altering the intestinal microbiota associated with microglial?…[]
Short-but no long-term effect of social stress in rodent depressive-like behavior is not affected by chronic treatment with Harmine[]
bioinformatics and biomedical engineering Blood Plasma Trophic Growth Factors Predict the Outcome in Patients with Acute Ischemic Stroke[]
Overektomize di?i s??anlarda beyin oksidatif stres, bdnf ve inflamatuar cevap düzeyleri ile n?rodavran??sal de?i?iklikler üzerine anjiyotensin II ?nhibisyonunun etkisi[]
EUROPEAN CHILD & ADOLESCENT PSYCHIATRYIncreased serum brain-derived neurotrophic factor and adrenocorticotropic hormone levels are associated with obsessive compulsive disorder in medication?free??-[33389158]
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRYSea urchin gangliosides exhibit neuritogenic effects in neuronal PC12 cells via TrkA- and TrkB-related pathways[33589896]
Neuropsychiatr Dis TreatRepetitive Transcranial Magnetic Stimulation Improves Mild Cognitive Impairment Associated with Alzheimer's Disease in Mice by Modulating the miR-567?…[34239303]
Einstein (Sao Paulo)Tropomyosin receptor kinase B-mediated signaling in integration of neuropathic pain and obesity in diabetic polyneuropathy[34586159]
Metab Brain DisModerate-intensity continuous training and high-intensity interval training improve cognition, and BDNF levels of middle-aged overweight men[34762211]
Transl PsychiatryLithium augmentation of ketamine increases insulin signaling and antidepressant-like active stress coping in a rodent model of treatment-resistant depression[34824208]
Iranian Journal of Basic Medical SciencesAdrenomedullin increases cAMP accumulation and BDNF expression in rat DRG and spinal motor neurons[34712429]
J Sex MedEndogenous Deficiency of Brain-Derived Neurotrophic Factor Induces the Downregulation of Tryptophan Hydroxylase-2 Expression in Raphe Nuclei of Rapid?…[34384732]
Cell Biochem FunctCNTs‐CaP/chitosan‐coated AZ91D magnesium alloy extract promoted rat dorsal root ganglia neuron growth via activating ERK signalling pathway[34296452]
J Endocrinol InvestSerum alpha-melanocyte-stimulating hormone (a-MSH), brain-derived neurotrophic factor (BDNF), and agouti-related protein (AGRP) levels in children with Prader?…[Pubmed:35098494]
Clinical RheumatologyGender influence on clinical manifestations, depressive symptoms and brain-derived neurotrophic factor (BDNF) serum levels in patients affected by?…[Pubmed:35344113]
Sci RepAssociations between serum levels of brain-derived neurotrophic factor, corticotropin releasing hormone and mental distress in vitiligo patients[Pubmed:35508633]
PharmaceuticsCo-Delivery of Docosahexaenoic Acid and Brain-Derived Neurotropic Factor from Electrospun Aligned Core–Shell Fibrous Membranes in Treatment of Spinal Cord?…[Pubmed:35214053]
Molecular Biology ReportsUmbilical cord-derived mesenchymal stem cell conditioned medium reverses neuronal oxidative injury by inhibition of TRPM2 activation and the JNK signaling?…[Pubmed:35585377]
Journal of Complementary Medicine ResearchEffect of herbal formulation Sharbat Ahmad Shahi on serum BDNF level in mild to moderate cases of depressive disorder[]
AFRICAN JOURNAL OF BIOCHEMISTRY RESEARCHMedicinal effects of Saffron on obese animals by reducing Castellis risk index to protect from cardio-pathology and psychological distress[]