胱天蛋白酶1(CASP1)多克隆抗體
Polyclonal Antibody to Caspase 1 (CASP1)
ICE; IL1BC; IL1-BC; P45; Interleukin 1 Beta Converting Enzyme; Apoptosis-Related Cysteine Peptidase; Interleukin-1 beta convertase
- 編號PAB592Ra01
- 物種Rattus norvegicus (Rat，大鼠)相同的名稱，不同的物種。
- 來源多抗制備
- 宿主兔
- 效價-
- Ig類型IgG
- 純化方式抗原特異性親和純化
- 標記物無標記物
- 免疫原RPB592Ra01-胱天蛋白酶1(CASP1)重組蛋白
- 緩沖液成份磷酸鹽緩沖液（pH7.4,含有0.02% NaN3和50%甘油）
- 性狀液體
- 濃度0.5mg/mL
- 且適物種Homo sapiens (Human，人), Mus musculus (Mouse，小鼠)
- 應(yīng)用WB
如果抗體需用于流式細胞術(shù)，請參見流式抗體。 - 下載英文說明書 中文說明書
- 規(guī)格20μl100μl200μl1ml10ml
- 價格¥ 652¥ 1520¥ 2172¥ 5430¥ 21720
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產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)
IHC圖
Figure. Western Blot; Sample: Recombinant CASP1, Rat.
Western Blot; Sample: Human Serum;
Primary Ab: 1μg/ml Rabbit Anti-Rat CASP1 Antibody
Second Ab: 0.2μg/mL?HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
(Catalog: SAA544Rb19)
Western Blot; Sample: Mouse Serum;
Primary Ab: 1μg/ml Rabbit Anti-Rat CASP1 Antibody
Second Ab: 0.2μg/mL?HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
(Catalog: SAA544Rb19)
Western Blot; Sample: Rat Liver lysate; <br/>Primary Ab: 1μg/ml Rabbit Anti-Rat CASP1 Antibody<br/>Second Ab: 0.2μg/mL?HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody<br/>(Catalog: SAA544Rb19)
Western Blot; Sample: Lane1: Rat Spleen lysate; Lane2: Rat Cerebrum lysate
Primary Ab: 0.2μg/ml Rabbit Anti-Rat CASP1 Antibody
Second Ab: 0.2μg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
(Catalog: SAA544Rb19)
Western Blot; Sample: Lane1: Rat Cerebrum lysate; Lane2: Mouse Spleen lysate
Primary Ab: 0.5μg/ml Rabbit Anti-Rat CASP1 Antibody
Second Ab: 0.2μg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
(Catalog: SAA544Rb19)
通過ISO 9001、ISO 13485質(zhì)量體系認證
特異性
該抗體是針對CASP1的兔多克隆抗體。在免疫組織化學染色和免疫印跡實驗中能識別CASP1。
用法
Western blotting: 0.01-2μg/mL;
Immunohistochemistry: 5-20μg/mL;
Immunocytochemistry: 5-20μg/mL;
Optimal working dilutions must be determined by end user.
儲存
經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復(fù)凍融。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當?shù)臈l件下存儲，損失率低于5%。
贈品
增值服務(wù)
相關(guān)產(chǎn)品
| 編號 | 適用物種：Rattus norvegicus (Rat，大鼠) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| APB592Ra01 | 胱天蛋白酶1(CASP1)活性蛋白 | Cell?culture;?Activity?Assays. |
| RPB592Ra01 | 胱天蛋白酶1(CASP1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAB592Ra01 | 胱天蛋白酶1(CASP1)多克隆抗體 | WB |
| LAB592Ra71 | 胱天蛋白酶1(CASP1)多克隆抗體(生物素標記) | WB |
| MAB592Ra21 | 胱天蛋白酶1(CASP1)單克隆抗體 | WB; IHC; ICC; IP. |
| SEB592Ra | 胱天蛋白酶1(CASP1)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMB592Ra | 胱天蛋白酶1(CASP1)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻
| 雜志 | 參考文獻 |
| PLoS One. | Cilostazol Renoprotective Effect: Modulation of PPAR-γ, NGAL, KIM-1 and IL-18 Underlies Its Novel Effect in a Model of Ischemia-Reperfusion[Pubmed:24816434] |
| Fertil Steril | Inflammosome in the human endometrium: further step in the evaluation of the “maternal side”[PubMed: 26474737] |
| PLoS One | Synthetic PreImplantation Factor (PIF) prevents fetal loss by modulating LPS induced inflammatory response.[pubmed:28704412] |
| Journal of?Virology | NS1 protein of 2009 pandemic influenza A virus inhibits porcine NLRP3 inflammasome-mediated interleukin-1 beta production by suppressing ASC ubiquitination[Pubmed:29386291] |
| Journal of Translational Medicine | Recurrent pregnancy loss is associated to leaky gut: a novel pathogenic model of endometrium inflammation?[Pubmed:29665864] |
| Reproductive?Sciences | A role for the inflammasome in spontaneous labor at term[Pubmed:27852921] |
| Journal?of?Virology | CHARACTERIZATION OF PORCINE NLRP3 INFLAMMASOME-MEDIATED INTERLEUKIN-1 BETA PRODUCTION IN RESPONSE TO INFLUENZA A VIRUSES[Pubmed: 29386291] |
| ACTA?Otorhinolaryngologica Italica | NLRP3 inflammasome expression in lipopolysaccharide-induced otitis media[Pubmed: 30676848] |
| American Journal of Reproductive Immunology | Effect of alpha lipoic acid and myoinositol on endometrial inflammasome from recurrent pregnancy loss women[Pubmed: 31148259] |
| Taiwanese Journal of Obstetrics & Gynecology | Serum Caspase-1 levels in women with polycystic ovary syndrome[Pubmed: 32127139] |
| Iranian Journal of Allergy, Asthma and Immunology | Increased Level of Caspase-1 in the Serum of Relapsing-remitting Multiple Sclerosis (RRMS) Patients[] |
| ACTIVITY OF APOPTOSIS MARKERS IN HPV-ASSOCIATED CERVICAL PATHOLOGIES[] | |
| Norwegian Journal of development of the International Science | CLINICAL AND PATHOGENETIC SIGNIFICANCE OF CHANGES IN PURINE METABOLISM DURING LUNG CANCER [] |
| LIFE SCIENCES | The NLRP3 inhibitor dapansutrile attenuates folic acid induced nephrotoxicity via inhibiting inflammasome/caspase-1/IL axis and regulating autophagy/proliferation[34560082] |
| Biol Reprod | The alarmin S100A12 causes sterile inflammation of the human chorioamniotic membranes and preterm birth and neonatal mortality in mice[34632484] |
| J Mol Neurosci | TRPV1 Suppressed NLRP3 Through Regulating Autophagy in Microglia After Ischemia-Reperfusion Injury[Pubmed:35041191] |
| Viruses | Influenza A Virus Infection Activates NLRP3 Inflammasome through Trans-Golgi Network Dispersion[Pubmed:35062292] |