肌酸激酶MB同工酶(CKMB)重組蛋白
Recombinant Creatine Kinase MB Isoenzyme (CKMB)
CK2; CK-MB; Creatine Kinase,Muscle/Brain
- 編號(hào)RPA479Hu01
- 物種Homo sapiens (Human，人)相同的名稱(chēng)，不同的物種。
- 來(lái)源原核表達(dá)
- 宿主E.coli
- 內(nèi)毒素水平<1.0EU/µg(LAL法測(cè)定)
- 亞細(xì)胞定位細(xì)胞質(zhì)
- 預(yù)測(cè)分子量90.1kDa
- 實(shí)際分子量90kDa(差異分析請(qǐng)參閱說(shuō)明書(shū))
- 片段與標(biāo)簽Pro2~Lys381+GGGGS*3+Pro2~Lys381 with N-terminal His Tag
- 緩沖液成份PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
- 性狀凍干粉
- 純度> 80%
- 等電點(diǎn)6.4
- 應(yīng)用Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請(qǐng)參見(jiàn)活性蛋白。 - 下載英文說(shuō)明書(shū) 中文說(shuō)明書(shū)
- 規(guī)格10μg50μg200μg1mg5mg
- 價(jià)格暫無(wú)報(bào)價(jià)暫無(wú)報(bào)價(jià)暫無(wú)報(bào)價(jià)暫無(wú)報(bào)價(jià)暫無(wú)報(bào)價(jià)
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產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)
Figure. SDS-PAGE
通過(guò)ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
序列
用法
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲(chǔ)存
避免反復(fù)凍融。2-8°C不超過(guò)一個(gè)月，-80°C不超過(guò)12個(gè)月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒(méi)有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲(chǔ)，損失率低于5%。
增值服務(wù)
相關(guān)產(chǎn)品
| 編號(hào) | 適用物種：Homo sapiens (Human，人) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| RPA479Hu01 | 肌酸激酶MB同工酶(CKMB)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| SEA479Hu | 肌酸激酶MB同工酶(CKMB)檢測(cè)試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMA479Hu | 肌酸激酶MB同工酶(CKMB)等多因子檢測(cè)試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻(xiàn)
| 雜志 | 參考文獻(xiàn) |
| Cardiovascular Toxicology | Aldehyde Dehydrogenase-2 Activation during Cardioplegic Arrest Enhances the Cardioprotection against Myocardial Ischemia–Reperfusion Injury[PubMed: 22814936] |
| PLoS One | N-Acetylcysteine and Allopurinol Confer Synergy in Attenuating Myocardial Ischemia Injury via Restoring HIF-1α/HO-1 Signaling in Diabetic Rats[PubMed: PMC3715528] |
| Int J Clin Exp Med | Effects of morphine and sufentanil preconditioning against myocardial ischemic-reperfusion injury in rabbits[PubMed: 26629064] |
| European Journal of Pharmacology | Diabetes blocks the cardioprotective effects of sevoflurane postconditioning by impairing Nrf2/Brg1/HO-1 signaling[Pubmed:26973173] |
| Asian Pac J Trop Med.? | Effect of levocarnitine on TIMP-1, ICAM-1 expression of rats with coronary heart disease and its myocardial protection effect[Pubmed:26972400] |
| Heart International | Circulating miR-126 and miR-499 reflect progression of cardiovascular disease; correlations with uric acid and ejection fraction[pubmed:27924211] |
| American Journal of Translational?Research | Peroxisome proliferator-activated receptor γ (PPARγ) mediates the protective effect of quercetin against myocardial ischemia-reperfusion injury via …[PMC5209473] |
| Archivum Immunologiae et Therapiae Experimentalis | In?Vivo?Cardioprotective?Effects?and?Pharmacokinetic?Profile?of?N-Propyl?Caffeamide?AgainstIschemia?Reperfusion?Injury.[pubmed:27480649] |
| Archivos de medicina veterinaria | Cardiac biomarkers in dogs with visceral leishmaniasis[S0301-732X2016000300004] |
| Cellular Physiology and Biochemistry | Remote Limb Ischaemic Postconditioning Protects Against Myocardial Ischaemia/ Reperfusion Injury in Mice: Activation of JAK/STAT3-Mediated Nrf2-Antioxidant Signalling[10.1159:481755] |
| Erciyes Medical Journal | Morinda Citrifolia (Noni) and Low Dose Aspirin Prevent Apoptotic Cell Death and Oxidative Stress on Isoproterenol Induced Myocardial Infarction in Rats[DOI: 10.5152/etd.2017.1732] |
| International Immunopharmacology | Metformin attenuated endotoxin-induced acute myocarditis via activating AMPK[pubmed:28410530] |
| Science?of the?Total?Environment | Co-exposure of silica nanoparticles and methylmercury induced cardiac toxicity and[Pubmed:29727991] |
| Journal of Surgical Research | GYY4137 protects against myocardial ischemia/reperfusion injury via activation of the PHLPP-1/Akt/Nrf2 signaling pathway in diabetic mice[Pubmed:29605032] |
| Molecular?Medicine?Reports? | Hydrogen?rich solution against myocardial injury and aquaporin expression via the PI3K/Akt signaling pathway during cardiopulmonary bypass in rats[Pubmed:29956781] |
| Cell?Death?Discovery | Cyclic helix B peptide ameliorates acute myocardial infarction in mice by inhibiting apoptosis and inflammatory responses[] |
| Oxidative Medicine and Cellular Longevity | Adiponectin Facilitates Postconditioning Cardioprotection through Both AMPK-Dependent Nuclear and AMPK-Independent Mitochondrial STAT3 Activation[Pubmed: 32190173] |
| PLoS One | Tissue suction-mediated gene transfer to the beating heart in mice[Pubmed: 32027678] |
| FASEB JOURNAL | Deletion of Rap1 protects against myocardial ischemia/reperfusion injury through suppressing cell apoptosis via activation of STAT3 signaling[Pubmed: 32020680] |
| Molecular Medicine Reports | Differentially expressed lncRNAs, miRNAs and mRNAs with associated ceRNA networks in a mouse model of myocardial ischemia/reperfusion injury[Pubmed: 32705277] |
| In Vivo | Hydrogen sulphide and nitric oxide cooperate in cardioprotection against ischemia/reperfusion injury in isolated rat heart[Pubmed: 32871779] |
| Drug Design Development and Therapy | Melatonin Attenuates Anoxia/Reoxygenation Injury by Inhibiting Excessive Mitophagy Through the MT2/SIRT3/FoxO3a Signaling Pathway in H9c2 Cells[Pubmed: 32546969] |
| Nanomaterials | Biological Safety and Biodistribution of Chitosan Nanoparticles[Pubmed: 32340313] |
| Molecular Medicine Reports | The mRNA expression of Il6 and Pdcd1 are predictive and protective factors for doxorubicin?induced cardiotoxicity[33300057] |
| Oxid Med Cell Longev | Inactivation of TOPK Caused by Hyperglycemia Blocks Diabetic Heart Sensitivity to Sevoflurane Postconditioning by Impairing the PTEN/PI3K/Akt Signaling[33986917] |
| Eur J Pharmacol | Long non-coding RNA MALAT1 modulates myocardial ischemia-reperfusion injury though the PI3K/Akt/eNOS pathway by sponging miRNA-133a-3p to target IGF1R?…[Pubmed:34968461] |
| Cardiovasc Drugs Ther | Hyperglycemia-Induced Overexpression of PH Domain Leucine-Rich Repeat Protein Phosphatase 1 (PHLPP1) Compromises the Cardioprotective Effect of Ischemic?…[Pubmed:35715527] |
| Nutrients | Mokko Lactone Alleviates Doxorubicin-Induced Cardiotoxicity in Rats via Antioxidant, Anti-Inflammatory, and Antiapoptotic Activities. Nutrients 2022, 14, 733[Pubmed:35215383] |
| Experimental and Therapeutic Medicine | Hydrogen therapy after resuscitation improves myocardial injury involving inhibition of autophagy in an asphyxial rat model of cardiac arrest[Pubmed:35495584] |
| Oxidative Medicine and Cellular Longevity | MicroRNA-503 Exacerbates Myocardial Ischemia/Reperfusion Injury via Inhibiting PI3K/Akt-and STAT3-Dependent Prosurvival Signaling Pathways[Pubmed:35620576] |
| International Journal of Sciences: Basic and Applied Research | Vitamin E Attenuates Cardiomyopathy Via Alleviation of Autophagic Stress[] |